The Sedia™ HIV-1 Limiting Antigen Avidity Enzyme Immunoassay, a leading HIV incidence assay, can now be used on dried blood specimens without need for cold chain storage.
Steve Piacentini, Sedia’s Director of Assay Development, and Senior Project Manager for the development of both HIV-1 LAg-Avidity EIAs, said, “We were very focused on developing a quality product that can be manufactured on a consistent basis, to ensure the continued supply of the assay for the ongoing needs of the CDC’s and other public health groups’ programs. Now with the extensive evaluations completed by CDC and the approval they have issued, we look forward to supplying this product to our other customers.”
Dr. Ronald W. Mink, Sedia’s President and Chief Science Officer stated, “We are delighted to be able to offer the Sedia™ HIV-1 Limiting Antigen (LAg)-Avidity EIA for DBS to programs reliant on collection of dried blood spots, enabling them to use this cutting edge technology to monitor and manage their programs. Providing this kind of information on these programs is critical to their long-term success in the battle against AIDS globally.”
The Sedia™ HIV-1 Limiting Antigen (LAg)-Avidity EIA including its DBS version, works by quantitatively measuring the maturation of the antibody response, measurind as antibody avidity or “binding strength”, as the HIV-1 infection progresses. Recently infected persons produce primarily low-avidity or low binding strength antibodies to the HIV-1 virus, and persons with longer term infections produce more high-avidity antibodies, allowing differentiation between new and established infections. Conventional diagnostic screening tests only indicate that the person is infected, not whether the disease is a new one or one that may have happened years earlier. Sedia Biosciences is the world’s leading manufacturer of commercial assays to measure HIV-1 incidence and identify recent infections.
Research reported in this press release was supported by a Small Business Innovation Research grant from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health under Award Number R44AI097001. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
September 21, 2015
Sedia Biosciences Corporation