Website TwistBioscience Twist Bioscience

We are looking for motivated, enthusiastic individuals to join our Twist Bioscience Operations Team in South San Francisco. The Manufacturing Associate, Vector Scale-Up will use standard Cellular and Molecular Biology techniques to produce high quality DNA through bacterial cell culture, DNA extraction and manipulation. The ideal candidate is a team player who can execute well established procedures in a safe and timely manner.

Roles and Responsibilities include but are not limited to:

Manufacture high quality custom oligo containing products in a high throughput MFG lab according to established SOPs.
Operation of robotic laboratory equipment and traditional lab equipment (bioanalyzers, centrifuges, sealers, thermocyclers, spectrometers, HPLCs, Next Gen Sequencing etc.)
Daily use of traditional molecular biology processes and techniques especially PCR, DNA quantitation and handling, DNA purification
Maintaining thorough, accurate and detailed documentation of all work produced in batch records, databases or other acceptable formats  including problems and deviations
Updating and writing work instructions and documentation
Ability to work independently and in a safe manner
Attention to details for process consistency
Documentation, troubleshooting and addressing process deviations
Packaging products
Ability to work in an ISO, GMP, LEAN manufacturing environment and follow the lean manufacturing concepts
Daily completion of assigned tasks to keep MFG on track

Focus Area for Custom Vector Onboarding:

Some experience with PCR, Restriction digest setup, Agarose gel electrophoresis
Familiar with aseptic technique
Is accustomed to following manufacturing batch records, reporting and documenting issues and deviations in the workflow
Detail oriented and organized
Has previously worked as part of a team

Key Skills/Qualifications

MA :0-1 year of relevant lab experience and/or Bachelors or Associates degree in biology, chemistry, biochemistry but will consider candidates with relevant laboratory experience
Familiarity with or prior experience in a manufacturing environment a plus
Ability to follow work instructions and SOPs to complete Manufacturing goals
MA II:2 or more years of relevant lab experience and/or Bachelors or Associates degree in biology, chemistry, biochemistry but will consider candidates with relevant laboratory experience
Familiarity with or prior experience in a manufacturing environment
Intermediate knowledge of and experience performing molecular biology techniques and processes
MA III:4 or more years of relevant lab experience and/or Bachelors or Associates degree in biology, chemistry, biochemistry but will consider candidates with relevant laboratory experience
Familiarity with or prior experience in a manufacturing environment
Advanced knowledge of and experience performing molecular biology techniques and processes
Ability to troubleshoot processes and escalate issues as appropriate
Advanced knowledge of Confluence
Ability to help create procedures or administrative controls and train operators
Required for all Levels:

Good written and verbal skills
Attention to details
Good computer skills and comfort in using computers for all aspects of MFG, experience with excel and word, Jira/Confluence, web based or similar programs

Typical Working Conditions are:

Team based laboratory environment.
Working in controlled laboratory environment
Must be able to stand for long periods of time while performing duties.
Must be able to work safely with chemicals and hazardous materials.
Must be able to lift up to 20 lbs.
Must be able to work outside of regular work hours/ work a flexible shift as needed
Available Shifts:

1A: Sunday -Tuesday, alt Wednesday, 7:00am-7:30pm

To apply for this job please visit www.twistbioscience.com.